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Fig. 5 | Journal of Inflammation

Fig. 5

From: Disulfiram alleviates acute lung injury and related intestinal mucosal barrier impairment by targeting GSDMD-dependent pyroptosis

Fig. 5

Disulfiram ameliorated lung inflammation in WT mice treated with LPS. (A) H&E staining of lung sections from indicated mice under x200 magnification (scale bar = 100 μm);(B) wet/dry Ratio of the lung, *P < 0.05, **P < 0.01, by Kruskal-Wallis test followed by Dunn’s Multiple Comparison Test; (C) Levels of the number of total cells, macrophages, and neutrophils in BALF, ***P < 0.001, ****P < 0.0001, by two-way ANOVA followed by post hoc Bonferroni’s Multiple Comparison Test; (D) Expression of TNF-α and IL-6 in serum. n = 10 for per group. *P < 0.05, **P < 0.01, ***P < 0.001, by one-way ANOVA followed by post hoc Newman-Keuls Multiple Comparison Test; NS means Not significant

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