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Fig. 5 | Journal of Inflammation

Fig. 5

From: SILAC-based quantitative proteomics to investigate the eicosanoid associated inflammatory response in activated macrophages

Fig. 5

Reactome Reactions network. A The log2-fold changes (n = 3 ± SD) in protein abundance between PBS control and [Kdo2-lipid A + ATP] treated RAW264.7 cells following SILAC are presented. B The number of identified genes per term along with associated term p-value corrected with Bonferroni step down is shown. C The network of Reactome reactions orthologies associated with the proteins with a significant fold change lower 0.5 (green) or higher than 2 (red) in relative abundance after stimulation with [Kdo2-lipid A + ATP] compared to a matched PBS control. Nodes (large circles) are linked by their common genes (red labels) based on a kappa score (≥ 0.4), with the label of the most significant terms displayed. Colour intensity of nodes represent significance of ontology

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