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Fig. 2 | Journal of Inflammation

Fig. 2

From: Human monocytes differentiate into tumor-associated macrophages upon SKOV3 cells coculture and/or lysophosphatidic acid stimulation

Fig. 2

The morphology of induced monocyte-derived cells under the conditions of coculture with SKOV3 cells and/or LPA stimulation was changed significantly compared to those of monocytes. Monocyte-derived cells cocultured with SKOV3 cells and/or stimulated with LPA (LPA5, SM and SM5) showed adherent cell growth, an increased size, an irregular shape, pseudopodia and protrusions. Notes: 1) MO: monocytes were cultured alone in LPA-free medium; 2) LPA5: monocytes were cultured alone in medium with 5 μM LPA; 3) SM: monocytes were cocultured with SKOV3 cells in LPA-free medium; and 4) SM5: monocytes were cocultured with SKOV3 cells in medium with 5 μM LPA

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