Fig. 4
From: Serinc2 deficiency causes susceptibility to sepsis-associated acute lung injury
Serinc2 KO aggravates CLP-induced apoptosis in the lung. A Representative TUNEL staining images (left) and quantification data (right) showing the impact of Serinc2 KO on CLP-induced apoptosis. **P < 0.01 vs. WT; ###P < 0.001 vs. sham. n = 5. B Immunoblots showing the impact of Serinc2 KO on CLP-induced changes of cleaved caspase-3, Bax, and Bcl2. C Quantification of cleaved caspase-3, Bax and Bcl2 expression relative to GAPDH. **P < 0.01 vs. WT; #P < 0.05, ##P < 0.01 vs. sham. n = 3. D Immunoblots showing the impact of Serinc2 KO on CLP-induced Akt phosphorylation. E Quantification of Akt phosphorylation relative to its total protein. *P < 0.05 vs. WT; #P < 0.05 vs. sham. n = 3