Fig. 7From: Influenza a virus triggers acute exacerbation of chronic obstructive pulmonary disease by increasing proinflammatory cytokines secretion via NLRP3 inflammasome activationThe role of IAV induced NLRP3 inflammasome activation in AECOPD. Invasion of IAV promotes the NLRP3 inflammasome activation in bronchial epithelial cell, which contribute to increase secretion of pro-inflammatory cytokines and triggers acute exacerbation of COPD; whereas MCC950 therapy reverse the progressionBack to article page