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Fig. 4 | Journal of Inflammation

Fig. 4

From: Prophylactic or therapeutic administration of Holarrhena floribunda hydro ethanol extract suppresses complete Freund’s adjuvant-induced arthritis in Sprague-Dawley rats

Fig. 4

Effect of treatment on serum levels of PKA, PKC and cAMP in control and adjuvant-induced arthritic rats. Sprague-Dawley rats were injected sub plantar with 0.1 ml of IFA or CFA into the right hind paw. The drug vehicle, dexamethasone (0.3 mg/kg) and HFE (50, 200, 500 mg/kg) were administered orally 1 h before arthritis induction and daily thereafter until the 28th day. Serum PKA (A), PKC (B) and cAMP (C) were assayed by ELISA. Data are presented as mean ± SEM of n ≥ 5. * (P ≤ 0.05), ** (P ≤ 0.01), *** (P ≤ 0.001) values significantly different when compared with CFA arthritic control group

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Journal of Inflammation

ISSN: 1476-9255

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