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Fig. 3 | Journal of Inflammation

Fig. 3

From: Prophylactic or therapeutic administration of Holarrhena floribunda hydro ethanol extract suppresses complete Freund’s adjuvant-induced arthritis in Sprague-Dawley rats

Fig. 3

Effect of treatment on serum levels of IL-1α, IL-6 and IL-10 in control and adjuvant-induced arthritic rats. Sprague-Dawley rats were injected sub plantar with 0.1 ml of IFA or CFA into the right hind paw. The drug vehicle, dexamethasone (0.3 mg/kg) and HFE (50, 200, 500 mg/kg) were administered orally 1 h before arthritis induction and daily thereafter until the 28th day. IL-1α (A), IL-6 (B) and IL-10 (C) were assayed by ELISA. Data are presented as mean ± SEM for n ≥ 5. * (P ≤ 0.05), *** (P ≤ 0.001) values significantly different when compared with CFA arthritic control group

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