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Fig. 2 | Journal of Inflammation

Fig. 2

From: Prophylactic or therapeutic administration of Holarrhena floribunda hydro ethanol extract suppresses complete Freund’s adjuvant-induced arthritis in Sprague-Dawley rats

Fig. 2

Arthritis score from photographs of arthritic Sprague-Dawley rats. The rats were injected sub plantar in the right hind paw with IFA or CFA. Vehicle, dexamethasone (0.3 mg/kg) or HFE treatment was administered 1 h before arthritis induction and daily thereafter until day 28 in the prophylactic model (left panel). In the therapeutic model, treatment was from day 14–28 (right panel). Arthritis scores were assigned on a scale of 0–4. The plots show scores as mean ± S.E.M of n ≥ 5. * (P ≤ 0.05), ** (P ≤ 0.01), *** (P ≤ 0.001), *** (P ≤ 0.0001) values significantly different from CFA arthritic control group

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