Fig. 4From: The functional characterization of phosphorylation of tristetraprolin at C-terminal NOT1-binding domainGeneration of TTP knockout RAW264.7 cells. A The homozygous and heterozygous KO cells were generated by double breaks of CRISPR/Cas9 genome editing in mouse RAW264.7 cells  using sgRNA-1 and sgRNA-4 as indicated. B TTP mRNA and protein expression in LPS-stimulated wild-type and TTP KO cellsBack to article page