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Fig. 3 | Journal of Inflammation

Fig. 3

From: AIM2 nuclear exit and inflammasome activation in chronic obstructive pulmonary disease and response to cigarette smoke

Fig. 3

Nuclear exit of AIM2 in lungs of COPD patients was coupled with IL-1β cleavage. a, b Representative confocal images of alveolar macrophages (a) and bronchiolar epithelium (b) in lung biopsies from non-COPD non-smoker controls (top) and COPD-III patients (bottom). Red: AIM2 by mouse mAb #1 (aa1–195); green: cleaved IL-1β; blue: DAPI. Magenta is the merged color of red and blue, indicating nuclear localization of AIM2. Yellow/orange is the merged color of red and green, indicating colocalization of AIM2 and cleaved IL-1β (short arrows). Scale bars are in micrometers

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