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Fig. 1 | Journal of Inflammation

Fig. 1

From: AIM2 nuclear exit and inflammasome activation in chronic obstructive pulmonary disease and response to cigarette smoke

Fig. 1

Nuclear and cytoplasmic AIM2. Representative confocal images revealing nuclear and cytoplasmic AIM2 detected with a rabbit polyclonal antibody (a, aa250–300/354, red by AF594) and a mouse monoclonal antibody (b, aa1–159, pseudogreen by AF647) in the same paraffin section of a human lung biopsies. Boxed areas are shown at magnification (right) to reveal cells having predominantly nuclear AIM2 (top box), or both nuclear and cytoplasmic AIM2 (bottom box). Blue is DAPI. Nuclear localization of AIM2 is indicated by the merged colors magenta in A and azure in B. Scale bars are in micrometers

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