Fig. 12From: Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathwaySignal transduction involving growth factors, receptor tyrosine kinases and members of the MAP kinase family. Esomeprazole-mediated activation of heme oxygenase 1 (HO1) involving phosphorylation of MEK, ERK and translocation of Nrf2 to control pro-inflammatory and profibrotic processes is illustratedBack to article page