Fig. 5
From: Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway
Pellino1 promoted inflammation in vivo model of lung injury by TRAF6/ NF-κB
Pellino1 protein induced TRAF6 and NF-κB protein expressions and TNF-α, IL-6, IL-1β and IL-18 levels in vivo model of lung injury (a, b, c, d, e, f and g); TRAF6 and NF-κB protein expressions and TNF-α, IL-6, IL-1β and IL-18 levels in Pellino1-/- mice model of lung injury (h, i, j, k, l, m and n)
Model, sepsis model group (n = 3); Model + Pellino1-/-, Pellino1−/− mice of sepsis model group (n = 3); Model + Pellino1, sepsis mice model by human recombinant Pellino1 protein group (n = 3). Data are presented as means ± SD using Student’s t test
##p < 0.01 compared with sepsis model group