Fig. 4
From: Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway
Pellino1 promoted inflammation in vitro model of lung injury by TRAF6/ NF-κB
Over-expression of Pellino1 induced Pellino1/TRAF6/ NF-κB protein expressions in vitro model (a, b, d and f); down-regulation of Pellino1 induced Pellino1/TRAF6/ NF-κB protein expressions in vitro model (b, c, e and g); over-expression of Pellino1 increased TNF-α, IL-6, IL-1β and IL-18 levels in vitro model (h, i, j and k); down-regulation of Pellino1 inhibited TNF-α, IL-6, IL-1β and IL-18 levels in vitro model (l, m, n and o)
Negative, negative group (n = 3); Pellino1, over-expression of Pellino1 group (n = 3); siPellino1, down-regulation of Pellino1 group (n = 3). Data are presented as means ± SD using Student’s t test
##p < 0.01 compared with negative group