Fig. 2
From: Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway
Knockout Pellino1 reduced lung injury and Pellino1 protein enhanced lung injury in sepsis mice
BAL neutrophil counts/mL (a), BAL protein concentrations (b), lung bacterial CFU/mL (c), circulating platelet counts (d), lung tissue by HE assay (e), BAL fluid hemoglobin (f), BAL fluid OD540 measurements at 0 h (g) and Evans blue dye measurements of lung tissue homogenates at OD620 (h) in Pellino1−/− mice;BAL neutrophil counts/mL (i), BAL protein concentrations (j), lung bacterial CFU/mL (k), circulating platelet counts (l), lung tissue by HE assay (m), BAL fluid hemoglobin (n, BAL fluid OD540 measurements at 0 h (o) and Evans blue dye measurements of lung tissue homogenates at OD620 (p)
Model, sepsis model group (n = 6); Model + Pellino1-/-, Pellino1−/− mice of sepsis model group (n = 6); Model + Pellino1, sepsis mice model by human recombinant Pellino1 protein group (n = 6). Data are presented as means ± SD using ANOVA followed by Tukey’s post hoc test
##p < 0.01 compared with sepsis model group