Fig. 2
From: Circular RNA-CDR1as acts as the sponge of microRNA-641 to promote osteoarthritis progression
CircRNA-CDR1as play a role in human OA chondrocytes. a Normal chondrocytes were transfected with circRNA-CDR1as siRNA. The expression level of circRNA-CDR1as was analyzed by qRT-PCR. b-c OA chondrocytes were transfected with circRNA-CDR1as siRNA or p-circRNA-CDR1as. Col II, MMP13 and IL-6 levels were analyzed by qRT-PCR and western blot. d Following transfection of siRNA, expression of COL II and MMP13 were assessed by immunofluorescence. Scale bar, 100 μm. Data are expressed as mean + SEM. *p < 0.05 (t-test). Shown are the representative results from at least 3 independent experiments