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Table 5 Correlation between anthropometric and biochemical parameters with gene expression of metabolic markers in children and adolescentsa

From: PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population

 

PPAR-α

p value

PPAR-β

p value

GLP-1R

p value

BMI

0,049

0,854

−0,257

0,354

−0,086

0,773

Arm fat (%)

0,052

0,850

−0,651**

0,013

−0,364

0,246

Leg fat (%)

0,208

0,438

−0,515

0,061

−0,266

0,404

Trunk fat (%)

0,096

0,723

−0,436

0,118

−0,322

0,309

Android fat (%)

−0,028

0,915

−0,339

0,231

−0,420

0,177

Gynoid fat (%)

0,108

0,690

−0,513

0,062

−0,189

0,546

Body fat (%)

0,096

0,723

−0,511

0,063

−0,343

0,276

Arm circumference

−0,094

0,713

0,306

0,266

−0,147

0,608

Arm muscle circumference

−0,173

0,501

0,411

0,128

0,042

0,892

Waist circumference (WC)

−0,308

0,226

0,050

0,860

0,059

0,844

Neck circumference

−0,048

0,852

0,190

0,496

0,090

0,758

Waist/Height ratio (WHR)

−0,262

0,291

−0,448

0,090

−0,326

0,241

Triceps skinfold

0,210

0,415

−0,390

0,146

−0,277

0,330

Subscapular skinfold

0,142

0,586

−0,225

0,413

0,183

0,527

Suprailiac skinfold

−0,429

0,084

0,285

0,301

−0,236

0,405

Abdominal skinfold

−0,712*

0,002

0,379

0,163

−0,678***

0,009

Fasting blood glucose

−0,364

0,149

0,340

0,214

−0,279

0,333

2 h glucose

0,042

0,876

− 0,412

0,125

− 0,051

0,868

Insulin

−0,185

0,471

0,293

0,287

−0,288

0,318

Total cholesterol

−0,021

0,934

0,075

0,790

0,209

0,473

Triglycerides

−0,247

0,335

−0,064

0,815

−0,125

0,671

HDL

0,416

0,098

−0,054

0,845

0,354

0,215

VLDL

−0,248

0,333

−0,064

0,815

−0,117

0,685

LDL

0,033

0,900

−0,086

0,756

0,077

0,797

HOMA-IR

−0,367

0,146

0,343

0,209

-0,341

0,234

TG/HDL ratio

-0,396

0,115

0,097

0,731

-0,182

0,532

  1. Spearman’s rank correlation test
  2. * p = 0.0016, ** p = 0.0132, *** p = 0.009
  3. a BMI body mass index, HDL high-density lipoprotein, VLDL very low-density lipoprotein, LDL low-density lipoprotein, HOMA-IR homeostatic model of assessment for insulin resistance