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Table 2 Biochemical and hormonal variables in children and adolescentsa

From: PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population

 

Control

Obesity

p value

 

n = 19

n = 18

 

Fasting blood glucose (mg/dL)

87,61 ± 5,55

87,59 ± 6,25

0,936

2 h glucose (mg/dL)

91,74 ± 13

94,23 ± 13,58

0,7617

Insulin (mcU/mL)

7,77 ± 4,78

19,77 ± 8,02

<  0,0001**

Total cholesterol (mg/dL)

150,15 ± 21,83

158,29 ± 24,91

0,3758

Triglycerides (mg/dL)

76,48 ± 18,47

117,27 ± 31,64

0,0001*

HDL (mg/dL)

50,34 ± 8,22

41,39 ± 9,51

0,0077*

LDL (mg/dL)

84,55 ± 18,04

94,70 ± 20,67

0,2547

VLDL (mg/dL)

15,29 ± 3,69

23,45 ± 6.33

0,0001**

HOMA-IR (score)

1,50 ± 1,19

4,28 ± 1,72

<  0,0001**

TG/HDL ratio

1,60 ± 0,61

3,02 ± 1,24

< 0,0001**

Android-gynoid % fat ratio

0,61 ± 0,17

0,99 ± 0,08

< 0,0001**

GLP-1 (ng/mL)

15,98 ± 0,69

17,70 ± 0,66

0,0725

GIP (pg/mL)

2637 ± 486,89

3137 ± 512,44

0,6299

  1. Values are presented as percentage or mean ± standard deviation (SD). Differences between groups were evaluated using Wilcoxon signed-rank tests
  2. * p < 0.005, ** p < 0.0001
  3. aHDL high-density lipoprotein, VLDL very low-density lipoprotein, LDL low-density lipoprotein, HOMA-IR homeostatic model of assessment for insulin resistance, GLP-1 glucagon-like peptide 1, GIP gastric inhibitory polypeptide