Fig. 4

Effect of dasatinib pre-treatment on markers of neutrophil degranulation in the alveolar space. a CD11b expression on BAL neutrophils, b MPO activity and c MPO concentration in BAL fluid from mice exposed to i.t. E. coli. *p < 0.05, **p < 0.01. Values were derived from two experiments (1 mg/kg or 10 mg/kg dasatinib vs. control administered at 0 and 12 h) using 8 mice per group. GMF = geometric mean fluorescence