Fig. 5

MAP results for colon biopsies. Statistical assessment of the differences observed in the abundance of selected cytokines between the study experimental groups and water control. Fold changes in the treatment groups (nicotine and anatabine at 5 and 20 mg/kg DSS) relative to water (control) are illustrated with colors ranging from blue (decrease) to red (increase). *, statistically significant differences on the basis of raw p-values < 0.05 (no adjustment has been made for multiple testing). Grey cells highlight missing estimates on the observed differences due to lack of cytokine quantifications. Nic 5, nicotine 5 mg/kg; Nic 20, nicotine 20 mg/kg; Ana 5, anatabine 5 mg/kg; Ana 20, anatabine 20 mg/kg