Fig. 2

CAA combined with high-dosage of VB6 regulated the expression of HMGB1, TLR4, NF-κB and inflammatory factors in traumatic rabbit’s model. a&b The mRNA expression of HMGB1 and TLR4 was detected by qRT-PCR. c&d The protein of HMGB1, TLR4, p-P65 and p65 was detected by Western blotting. e-g The concentrations of TNF-α, IL-6 and IL-1β were measured by ELISA. All the results were shown as mean ± SD (n = 3). * p < 0.05, ** p < 0.01 and *** p < 0.001