Skip to main content

Table 1 Baseline physiological parameters and CPR characteristics in groups

From: N-acetylcysteine alleviates post-resuscitation myocardial dysfunction and improves survival outcomes via partly inhibiting NLRP3 inflammasome induced-pyroptosis

Variables

Sham

(n = 12)

CPR

(n = 24)

CPR + NAC

(n = 24)

Body weight (g)

517 ± 22

514 ± 21

521 ± 15

Blood temperature (°C)

36.9 ± 0.3

36.8 ± 0.2

36.7 ± 0.3

Heart rate (beats/min)

411 ± 27

410 ± 29

409 ± 26

ETCO2 (mm Hg)

42 ± 3

42 ± 2

42 ± 3

MAP (mm Hg)

120 ± 7

119 ± 10

120 ± 6

Arterial PH

7.40 ± 0.04

7.40 ± 0.03

7.40 ± 0.04

EF (%)

71

74

73

CO (ml/min)

114

115

112

MPI

0.604

0.602

0.611

Rate of ROSC

–

20/24

21/24

CPP in PC1 (mm Hg)

–

25.1 ± 1.2

25.4 ± 1.1

CPP in PC3 (mm Hg)

–

24.9 ± 1.3

24.2 ± 1.7

CPP in PC7 (mm Hg)

–

32.2 ± 1.8

32.1 ± 2.1

  1. CPR Cardiopulmonary Resuscitation, NAC N-Acetylcysteine, ETCO2 End-Tidal CO2, MAP Mean Arterial Pressure, PH Potential of Hydrogen, EF Ejection Fraction, CO Cardiac Output, MPI Myocardial Performance Index, ROSC Restoration of Spontaneous Circulation, CPP Coronary Perfusion Pressure, PCn n minute after Precordial Compression,