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Fig. 4 | Journal of Inflammation

Fig. 4

From: N-acetylcysteine alleviates post-resuscitation myocardial dysfunction and improves survival outcomes via partly inhibiting NLRP3 inflammasome induced-pyroptosis

Fig. 4

Expressions of NLRP3, ASC, Cleaved-Caspase-1, and GSDMD, and the effect of NAC on myocardial pyroptosis after ROSC. a Representative western blotting images of NLRP3, ASC, Cleaved-Caspase-1, and GSDMD proteins in the myocardial tissues at 6 h after ROSC. b Quantitative protein analysis of NLRP3, ASC, and Cleaved-Caspase-1, and GSDMD expression in the three groups at 6 h after ROSC. The columns represent means ± SD of three independent experiments. NAC, N- acetylcysteine; CPR group, n = 16; CPR + NAC treatment group, n = 16; Sham group, n = 12. * p < .05 vs. Sham group, *p < .05 vs. CPR + NAC group

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