TY - JOUR AU - Tran, Hai B. AU - Macowan, Matthew G. AU - Abdo, Adrian AU - Donnelley, Martin AU - Parsons, David AU - Hodge, Sandra PY - 2020 DA - 2020/04/21 TI - Enhanced inflammasome activation and reduced sphingosine-1 phosphate S1P signalling in a respiratory mucoobstructive disease model JO - Journal of Inflammation SP - 16 VL - 17 IS - 1 AB - Inflammasomes and sphingosine-1-phosphate (S1P) signalling are increasingly subject to intensive research in human diseases. We hypothesize that in respiratory muco-obstructive diseases, mucus obstruction enhances NLRP3 inflammasome activation and dysregulated S1P signalling. SN - 1476-9255 UR - https://doi.org/10.1186/s12950-020-00248-2 DO - 10.1186/s12950-020-00248-2 ID - Tran2020 ER -