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Fig. 3 | Journal of Inflammation

Fig. 3

From: Urolithin a attenuates IL-1β-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-κB signaling pathways in rat articular chondrocytes

Fig. 3

Effect of UA on IL-1β induced degradation of Sox-9, Collagen II, and Aggrecan. Chondrocytes were treated with IL-1β (20 ng/ml) alone or UA (1, 7.5, and 15 μM) in combination with IL-1β (20 ng/ml) for 24 h. a Protein expression of Sox-9, Collagen II, and Aggrecan were determined by western blot. b, c, d Relative protein expression of Sox-9, Collagen II, and Aggrecan shown as histograms. Data are presented as mean ± S.D. n = 6. *P < 0.05, **P < 0.01, ***P < 0.001 versus the IL-1β group

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Journal of Inflammation

ISSN: 1476-9255

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