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Fig. 3 | Journal of Inflammation

Fig. 3

From: The role of SOCS3 in the hypothalamic paraventricular nucleus in rat model of inflammatory pain

Fig. 3

The effects of intra-PVN injection of AAV overexpressing SOCS3 (SOCS3-AAV) on inflammatory pain in the chronic phase in rats. (a)(b) The effects of intra-PVN injection of SOCS3-AAV on TWL and MWT in rats receiving CFA. (two-way ANOVA, n = 6). (c) The expression of SOCS3 in PVN in rats receiving CFA on day 7 after intra-PVN injection of SOCS3-AAV and SOCS3-CON (unpaired t-test, n = 6). (d) Representative images of c-fos in the PVN. SOCS3-AAV group presented a significant decrease in the number of c-fos-positive neurons in PVN versus SOCS3-CON group (unpaired t-test, n = 8). *P < 0.5 vs. SOCS3-CON group

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