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Fig. 2 | Journal of Inflammation

Fig. 2

From: The role of SOCS3 in the hypothalamic paraventricular nucleus in rat model of inflammatory pain

Fig. 2

The effects of intra-PVN injection of IL-6 neutralizing antibody on inflammatory pain in the acute phase in rats. (a) The effects of intra-PVN injection of IL-6 neutralizing antibody on TWL (one-way ANOVA, n = 6). (b) The expression of SOCS3 protein in PVN on day 7 after CFA administration (unpaired t-test, n = 6). (c)(d) Representative images of c-fos and Iba-1. IL-6 NA group presented a significant decrease in the number of c-fos-positive and Iba-1-positive neurons in PVN versus PBS group (unpaired t-test, n = 6). *P < 0.5 vs. PBS group

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