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Fig. 2 | Journal of Inflammation

Fig. 2

From: The double edge of anti-CD40 siRNA therapy: It increases renal microcapillar density but favours the generation of an inflammatory milieu in the kidneys of ApoE−/− mice

Fig. 2

Anti-CD40 siRNA treatment increases macrophage infiltration in the kidneys of treated mice. Representative images of F4-80/haematoxylin staining of kidney sections from ApoE−/− mice treated with: a control vehicle (veh), b a control sequence-scrambled siRNA (siSC), or c the anti-CD40 siRNA (siCD40), at 200x magnification (Scale bars are100 μm). G shows the renal glomeruli and a number of positive cells are marked by arrows. d Box-plot showing the number of F4/80+ cells per kidney section. Each diagram represents the median, quartiles and outliers. The colored box represents the interquartile range that contains 50% of the values. The whiskers are lines that extended from the box to the highest and lowest values, excluding outliers. A line across the box represents the median value. Kruskal Wallis test

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