Fig. 5
From: Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus
Expression of mRNA for ECM genes by conditionally immortalised mesangial cells following stimulation with lupus nephritis patient sera. Conditionally immortalised MCs were treated with 10% sera from patients with active (rBILAG A/B) and inactive (rBILAG D/E) LN and with age-and sex-matched HCs for 24 h. mRNA expression was assessed for COL1A1 (a), COL1A2 (b), COL3A1 (c), COL4A1 (d), LAMB1 (e) and LAMB2 (f). N = 5–6 per group, data are analysed using Kruskal-Wallis test with Dunn’s post-hoc test, *P < 0.05 vs untreated MCs