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Fig. 4 | Journal of Inflammation

Fig. 4

From: Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus

Fig. 4

Expression of mRNA for remodelling enzymes genes by conditionally immortalised mesangial cells following cytokine stimulation. Conditionally immortalised MCs were treated with IL-1β, TNF-α, IFN-α and IFN-γ alone and in combination (Combo) for 24 h. mRNA expression was assessed for MMP2 (a), MMP9 (b), and TIMP1 (c). N = 5 per group, data are analysed using Friedman’s test with Dunn’s post-hoc test, *P < 0.05 vs control

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