Fig. 2

Effect of preconditioning with different solution before LPS injection. Balb/c mice were divided into groups: LPS (received a lethal dose of 15 mg/kg of LPS); HS + LPS (received 4 mL/kg on the first day, then 6 mL/kg on the third day and 8 mL/kg on the fifth day of Hypertonic Saline 7.5%, then on the eighth day a lethal dose of 15 mg/kg of LPS); HU + LPS (received 4 mL/kg on the first day, then 6 mL/kg on the third day and 8 mL/kg on the fifth day of Urea 45%, then on the eighth day a lethal dose of 15 mg/kg of LPS); HB + LPS (received 4 mL/kg on the first day, then 6 mL/kg on the third day and 8 mL/kg on the fifth day of Sorbitol 45%, then on the eighth day a lethal dose of 15 mg/kg of LPS). * p < 0,05 vs LPS group; were used 20 animals for each group