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Table 2 Correlations between aqueous humor factors/cytokines and aqueous flare values at baseline and at the first recurrence

From: Anti-vascular endothelial growth factor agent reduces inflammation in macular edema with central retinal vein occlusion

Aqueous factors/Cytokines

sVEGFR-1

sVEGFR-2

VEGF

PlGF

PDGF-AA

sICAM-1

MCP-1

IL-6

IL-8

IL-12(p70)

IL-13

Variable

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

Aqueous flare at Baseline

0.71

< 0.001

0.33

0.151

0.70

< 0.001

0.45

0.043

0.49

0.033

0.50

0.031

0.58

0.011

0.47

0.035

0.67

0.003

0.11

0.627

0.10

0.659

Aqueous flare at 1st Recurrence

0.51

0.047

0.42

0.097

0.67

0.005

0.51

0.041

0.14

0.592

−0.05

0.849

0.36

0.166

0.59

0.022

0.71

0.002

0.32

0.203

0.36

0.170

  1. sVEGFR soluble vascular endothelial growth factor receptor, VEGF vascular endothelial growth factor, PlGF placental growth factor, PDGF platelet-derived growth factor, sICAM soluble intercellular adhesion molecule, MCP monocyte chemotactic protein, IL interleukin, r = correlation coefficient. Spearman’s rank-order correlation coefficients were calculated