Table 2 Anti-inflammatory agents that may prevent or reduce SIXR

Anti-complement agents

IL-6, IL-8, MCP-1

↓

[13]

IL-6 receptor blockade

fT3, IL-6, MCP-1

↑

[6, 13, 19, 26, 30]

Histones, C-RP, SAA

↓

[19, 26]

IL-6 inhibitor

C-RP

↓

[112]

TNF-α inhibitor

E-selectin, VCAM-1

↓

[113]

NF-κB inhibitor

(parthenolide)

Platelet aggregation, endothelial cell apoptosis

↓

[26, 114]

Alpha-1 antitrypsin (AAT)

IL-8, IL-1β, TNF-α

↓

[115]

Platelet inhibitor (aspirin)

IL-6

↓

[116]

T₃

Adenosine phosphate, creatine phosphate, lactate

↓

[88, 117, 118]

Glycogen

↑

TNF-α, IL-6

↓

[119]