Table 1 Current definition of ARDS: the Berlin definition [3]
From: Biomarkers for Acute Respiratory Distress syndrome and prospects for personalised medicine
Timing | Within 1 week of a known clinical insult or new or worsening respiratory symptoms | |
|---|---|---|
Chest imaging (chest radiograph or computed tomography scan) | Bilateral opacities; not fully explained by effusions, lobar/lung collapse, or nodules | |
Origin of edema | Respiratory failure not fully explained by cardiac failure or fluid overload Need objective assessment (e.g., echocardiography) to exclude hydrostatic edema if no risk factor present | |
Oxygenation | Mild | 200 mmHg < PaO2/FIO2 ≤ 300 mmHg with PEEP or CPAP ≥5 cmH2O |
Moderate | 100 mmHg < PaO2/FIO2 ≤ 200 mmHg with PEEP ≥5 cmH2O | |
Severe | PaO2/FIO2 ≤ 100 mmHg with PEEP ≥5 cmH2O | |