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Table 5 Multivariate linear regression analysis of circulating IgG against cytokines in atherosclerosis

From: Circulating natural antibodies to inflammatory cytokines are potential biomarkers for atherosclerosis

Factors

Adjusted R2

P value*

β & 95% CI

IL1β-1

 Male

−0.001

0.866

−0.007 (− 0.093, 0.078)

 Female

−0.008

0.481

0.039 (−0.071, 0.150)

 Total

−0.004

0.698

0.013 (−0.054, 0.081)

IL6

 Male

−0.006

0.736

0.016 (−0.075, 0.107)

 Female

0.003

0.179

0.098 (−0.045, 0.242)

 Total

0.001

0.204

0.052 (−0.029, 0.133)

IL8

 Male

−0.009

0.915

−0.004 (− 0.081, 0.073)

 Female

0.003

0.316

0.045 (− 0.043, 0.132)

 Total

−0.001

0.564

0.017 (−0.041, 0.074)

TNFα-1

 Male

0.012

0.161

0.051 (−0.021, 0.124)

 Female

0.073

< 0.001

0.157 (0.076, 0.239)

 Total

0.038

< 0.001

0.098 (0.044, 0.152)

IL1α

 Male

0.012

0.146

0.030 (−0.011, 0.071)

 Female

0.044

0.003

0.071 (0.024, 0.118)

 Total

0.025

0.002

0.048 (0.017, 0.079)

IL1β-2

 Male

0.009

0.988

−0.0004 (−0.056, 0.055)

 Female

0.023

0.026

0.083 (0.010, 0.155)

 Total

0.017

0.111

0.036 (−0.008, 0.080)

TNFα-2

 Male

0.012

0.215

−0.074 (− 0.192, 0.044)

 Female

−0.011

0.928

−0.006 (− 0.131, 0.120)

 Total

0.006

0.316

−0.044 (− 0.130, 0.042)

  1. *Adjusted P-value for age in male and female samples, and for gender and age in combined samples; CI confidence interval