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Table 2 MSO increases survival in a mouse model of inflammatory liver failure

From: In vitro suppression of inflammatory cytokine response by methionine sulfoximine

 

Alive

Dead

Total (n)

Percent Survival (%)

p a

Saline

3

19

22

14

–

L,S MSO (25 mg/kg)

19

9

28

68

0.0002

L,R MSO (25 mg/kg)

18

12

30

60

0.0013

  1. 24 h survival analysis of mice injected with saline, L,R MSO (25 mg/kg), or L,S MSO (25 mg/kg) 3 h prior to injection of LPS (20 μg/kg) and D-Galactosamine (800 mg/kg). a = determined by Fisher’s exact test
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Journal of Inflammation

ISSN: 1476-9255

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