Fig. 2From: Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosusProtein levels of NEK7, NLRP3 inflammasome components, and downstream cytokines in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients and healthy controls, as examined by western blotting and statistically analyzed by the Mann-Whitney U test. Compared to those in healthy controls, SLE patients showed lower protein levels of NEK7 and NLRP3, but higher levels of Caspase-1, IL-1b and IL-18. NEK7 (a); NLRP3 (b); ASC (c); Caspase-1 (d); IL-1b (e); IL-18 (f)Back to article page