CXCR-4 expression by circulating endothelial progenitor cells and SDF-1 serum levels are elevated in septic patients

Table 1 Clinical characteristics of patients and controls

Characteristics	Healthy controls	ICU controls	Septic patients
number of subjects	15	11	30
Age (years)
Mean ± SD	60,4 ± 14,3^a	57,8 ± 14,2	35,8 ± 12,9
Gender
Male (%)	3 (20)	6 (54,5)	20 (66,6)
Female (%)	12 (80)	5 (45,5)	10 (33,3)
Mortality < 28 days (%)		0 (0)	15 (50)
Mean SAPS II score (range)		38,8 (15–59)	49,9 (22–74)
Type of infection n (%)
Pneumonia			7 (23)
Peritonitis			9 (30)
Meningitis			4 (13)
Pancreatitis			1 (3)
Gastrointestinal tract			3 (10)
Necrotic fasciitis			2 (7)
Cholangitis			2 (7)
Cholecystitis			1 (3)
Trauma			1 (3)
WBC (×10⁹/L)		10.5	15.5
PCT (ng/ml)		1,9	22,9^a

Clinical data of study participants for age, gender, mortality, Simplified Acute Physiology Score (SAPS) II score, type of infection, white blood cell (WBC) count and procalcitonin (PCT) refer to the time point of blood sampling. ^aThe mean age in the group of healthy controls was significantly lower compared to the patient groups (p = 0.0001). There was no statistical difference in mean age between the two patient groups (p = 0,61). There was a significant difference in PCT levels between septic patients and ICU controls (p = 0,0002)

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