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Fig. 4 | Journal of Inflammation

Fig. 4

From: Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsis

Fig. 4

Atorvastatin or diacerein attenuate JNK and IRS phosphorylation in liver and muscle of septic animals. Phosphorylation of JNK in liver (a-b), muscle (c-d) after Atorvatatin or Diacerein treatment of sham and septic rats. Total protein expression of JNK. Serine 307 Phosphorylation of IRS1 in liver (a-b), muscle (c-d) after Atorvatatin or Diacerein treatment of septic rats. Total protein expression of IRS-1. The amount of protein loaded was 30 μg. Data are presented as means ± SEM from 6 rats per group. *P < 0.05 (Sepsis/Sal vs. all others groups). IB, immunoblot; C: Sham/Saline; Sal: Saline: Ator: Atorvastatin; Diac: Diacerein; ShT: Sham treatment

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