Fig. 4From: Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsisAtorvastatin or diacerein attenuate JNK and IRS phosphorylation in liver and muscle of septic animals. Phosphorylation of JNK in liver (a-b), muscle (c-d) after Atorvatatin or Diacerein treatment of sham and septic rats. Total protein expression of JNK. Serine 307 Phosphorylation of IRS1 in liver (a-b), muscle (c-d) after Atorvatatin or Diacerein treatment of septic rats. Total protein expression of IRS-1. The amount of protein loaded was 30 μg. Data are presented as means ± SEM from 6 rats per group. *P < 0.05 (Sepsis/Sal vs. all others groups). IB, immunoblot; C: Sham/Saline; Sal: Saline: Ator: Atorvastatin; Diac: Diacerein; ShT: Sham treatmentBack to article page