Fig. 1

DSS caused symptoms of inflammation on mouse model and miR-135a was over-expressed in DSS-induced colitis. To determine severity of inflammation, a body weight was evaluated; b H&E staining of tissue and c TUNEL assay were conducted. To determine expression of miR-135a, d qRT-PCR and e in situ hybridization were conducted. miR-135a: microRNA-135a, DSS-induced colitis: Dextran sulfate sodium-induced colitis; H&E staining, hematoxylin and eosin staining; TUNEL assay, terminal transferase uridyl nick end labelling assay; qRT-PCR, quantitative reverse transcription-PCR. ^***p < 0.001