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Fig. 2 | Journal of Inflammation

Fig. 2

From: Interleukin-10 attenuates impairment of the blood-brain barrier in a severe acute pancreatitis rat model

Fig. 2

IL-10 attenuated the down-regulation of claudin-5 in the brain of SAP rats. A. Immunohistochemistry of claudin-5 in SAP rat brains (× 400). Control groups exhibit high expression of claudin-5 in BMECs (i). Expression of claudin-5 decreased remarkably in the SAP group compared to the control group (ii). IL-10 attenuated the decreased expression of claudin-5 observed in the SAP group (iii). B. Representative WB images showing claudin-5 expression in SAP rat brains (a). WB analysis of claudin-5 expression (n = 8, b). * p < 0.01 (t-test), versus the control group, # p < 0.05 (t-test), versus the SAP group

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Journal of Inflammation

ISSN: 1476-9255

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