Treatment with 24 h–delayed normo- and hyperbaric oxygenation in severe sepsis induced by cecal ligation and puncture in rats

Table 4 Differences in median IL-10 concentration

Hours	HBO₂	NBO₂	Control
0	64.7 (0.1–148.5)	0.1 (0.1–278.8)	79.4 (0.1–155.9)
24	591.0 (336.2–969.1)	405.8 (296.6–579.9)	517.2 (289.6–1138)
48	489.4 (332.7–650.1)*	337.8 (203.6–453.4)	228.6 (40.4–313.2)*
72	250.9 (99.4–330.5)	72.5 (0.1–538.5)	169.5 (585.8–0.1)

IL interleukin, CLP cecal ligation and puncture, NBO ₂ normobaric oxygen treatment, HBO ₂ hyperbaric oxygen treatment
Values denote medians with IQR. Comparisons were performed using the Mann-Whitney U-test
*: p = 0.01 comparing parameter in HBO₂ vs. control. No other significant differences (p < 0.05) were found comparing HBO₂ with NBO₂ and HBO₂ with control

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