Treatment with 24 h–delayed normo- and hyperbaric oxygenation in severe sepsis induced by cecal ligation and puncture in rats

Table 3 Differences in median IL-6 concentration

Hours	HBO₂	NBO₂	Control
0	2.8 (2.8–30.5)	2.8 (2.8–153.2)	33.4 (2.8–70.0)
24	161.5 (14.6–296.5)	197.9 (2.8–278.6)	144.3 (53.4–322.9)
48	2.8 (2.8–77.9)	2.8 (2.8–101.3)	2.8 (2.8–95.5)
72	5.5 (2.8–134.9)	2.8 (2.8–224.7)	2.8 (2.8–182.6)

IL interleukin, CLP cecal ligation and puncture, NBO ₂ normobaric oxygen treatment, HBO ₂ hyperbaric oxygen treatment
Values denote medians with IQR. Comparisons were performed using the Mann-Whitney U-test. No significant differences (p < 0.05) were found comparing HBO₂ with NBO₂ and HBO₂ with control

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