Table 2 Gene ontology analysis for upregulated genes in the bronchiolar epithelium of bleomycin-treated mice with naphthalene-induced club cell injury compared to that without cell injury on day 14
From: Depletion of club cells attenuates bleomycin-induced lung injury and fibrosis in mice
Pathway | Frequency (%) | P value | FDR (%) |
|---|---|---|---|
Cytokine–cytokine receptor interaction | 3.53 | 2.55 × 10−15 | 3.12 × 10−12 |
Extracellular matrix–receptor interaction | 1.25 | 3.95 × 10−6 | 0.005 |
Complement and coagulation cascades | 1.14 | 9.85 × 10−6 | 0.012 |