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Table 2 Patient characteristics at ICU admission

From: Leptin independently predicts development of sepsis and its outcome

 

Men

Women

p

n = 57

n = 95

 

Age years

60.5(57.6–63.4)

56.3 (53.4–59.2)

0.02

Time between survey and sepsis years (median)

7.8 (IQR 8.3)

6.6 (IQR 8.1)

0.16

Disease scores

 APACHE II Score

18.2 (16.3–20.1)

18.9 (17.4–20.3)

0.57

 SOFA score

7.0 (6.0–8.0)

7.0 (6.2–7.8)

0.95

Disease severity n (%)

 Sepsis

17 (29.8)

22 (23.2)

0.44

 Severe sepsis

32 (56.1)

47 (49.5)

0.50

 Septic shock

8 (14.0)

26 (27.4)

0.07

 Hospital mortality

13 (22.8)

19 (20.0)

0.69

Co-morbidities n (%)

 COPD

1 (1.8)

3 (3.2)

1.00

 Congestive heart failure

3 (5.3)

2 (2.1)

0.36

 Chronic renal insufficiency

2 (3.5)

2 (2.1)

0.63

Diabetes n (%)

 Insulin treatment

4 (7.0)

7 (7.4)

1.00

 Other treatments

4 (7.0)

5 (5.3)

0.73

Cancer n (%)

 Hematological

4 (7.0)

5 (5.3)

0.73

 Localized

9 (15.8)

11 (11.6)

0.47

 Metastatic

5 (8.8)

6 (6.3)

0.75

Immunosuppressants n (%)

 Chronic steroids

3 (5.3)

5 (5.3)

1.00

 Chemotherapy

7 (12.3)

6 (6.3)

0.24

 Other immunosuppression

4 (7.0)

7 (7.4)

1.00

Primary infection site n (%)

 Pneumonia

11 (19)

13 (14)

0.37

 Abdominopelvic

19 (33)

31 (33)

1.00

 Urinary tract

10 (18)

11 (12)

0.34

 Other

17 (30)

38 (40)

0.23

 Unknown

2 (3.5)

3 (3.2)

1.00

  1. Values shown are means (95% CI), medians (IQR) and numbers (%)
  2. Abbreviations: APACHE acute physiology, age and chronic health evaluation, SOFA sequential organ failure assessment, CI confidence interval, IQR interquartile range, COPD chronic obstructive pulmonary disease, ICU intensive care unit