Fig. 2
From: Leptin independently predicts development of sepsis and its outcome
Leptin a baseline survey as predictor for sepsis. Values shown are odds ratios (OR) with 95% confidence intervals for leptin levels at baseline survey and the risk for a future sepsis event. Leptin were categorized into quartiles based on the cohort and sex-specific distribution amongst referents. The ORs represent the increased risk associated with the upper quartile of leptin (Q4) versus the reference (OR 1.00, lower three quartiles (Q1_3)). Model 1 included BMI, and model 2 included BMI, hypertension, reduced glucose tolerance (IFG, IGT a/o DM), and total cholesterol. Footnote: Cut-offs Q1_3 versus Q4 in absolute values for the different cohorts stratified for sex are for leptin (ng/mL): MONICA; 6.7 (only men): VIP; men 5.3, women 19.4: MSP 22.2 and NSMC 6.0 (only women in both) and for adiponectin (mg/mL): MONICA; 14.2 (only men): VIP; men 9.3, women 10.8: MSP 13.3 and NSMC 23.5 (only women in both)Abbreviations: MONICA, the Northern Sweden MONItoring Of trends and Determinants in CArdivascular Disease; VIP, Västerbotten Intervention Program; MSP, the Mammary Screening Program; NSMC, Northern Sweden Maternity Cohort