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Table 1 Population characteristics

From: Red cell distribution width (RDW) as a biomarker for respiratory failure in a pediatric ICU

 

All patients

Ventilation subgroup

Mean difference (95% CI)

P

Patients included (n)

960

333

  

Gender (male/female, %)

56/44

59/41

  

Age (years)

3.0 (<1–9.0)

2.0 (<1–6.0)

−1.6 (−2.2 –0.9)

<0.001

Age group (n, %)

  < 1 year

259 (27.0)

112 (33.6)

  

 1–5 years

245 (25.5)

133 (40.0)

  

 6–12 years

334 (34.8)

54 (16.2)

  

  > 12 years

122 (12.7)

34 (10.2)

  

Weight (kg)

14.0 (8.5–28.0)

12.0 (6.9–20.0)

–5.0 (−7.3–2.7)

<0.001

PRISM score

10.0 (4.0–15.0)

17.0 (13.0–23.0)

11.2 (10.4–12.1)

< 0.001

Reason for admission (%)

 Respiratory

25.0

30.3

  

 Trauma

9.9

9.9

  

 Postoperative

21.9

16.2

  

 Neurological

23.9

26.4

  

 Cardiac

3.2

5.7

  

 Renal

2.4

1.5

  

 Gastro-intestinal

2.1

0.9

  

 Intoxication

3.3

2.4

  

 Endocrinological

1.0

0.6

  

 Other

7.3

6.0

  

Admission parameters

 Hb (mg/dL)

10.8 (9.5–12.1)

10.0 (9.0–11.4)

−0.8 (−1.1 −0.6)

< 0.001

 Steroids (%)

15.2

17.1

 

0.23

 Vasopressors/inotropics (%)

6.4

14.2

 

<0.001

 Anaemia (%)

54.4

64.3

 

<0.001

 CRP (mg/dL)

19.0 (4.0–67.4)

22.7 (7.9–77.5)

7.6 (−3.0–18.0)

0.16

 WBC count (× 109/L)

11.6 (8.1–16.1)

10.7 (7.2–15.9)

-0.6 (−1.5–0.35)

0.21

RDW on admission

13.8 (13.0–15.1)

14.2 (13.1–15.3)

0.4 (0.1–0.6)

0.002

ICU LOS (days)

2.5 (1.0–5.8)

6.6 (2.5–13.9)

8.9 (7.8–10.0)

< 0.001

ICU mortality (%)

4.3

10.2

 

< 0.001

RDW on admission quintiles (n, %)

 Quintile 1 (11.2–12.8)

181 (18.8)

49 (14.7)

  

 Quintile 2 (12.9–13.4)

209 (21.7)

65 (19.5)

  

 Quintile 3 (13.5–14.3)

198 (20.6)

66 (19.8)

  

 Quintile 4 (14.4–15.4)

189 (19.7)

78 (23.4)

  

 Quintile 5 (15.5–29.6)

183 (19.1)

75 (22.5)

  

28 day VFD

 

23.0 (15.0–26.0)

  

Nadir P/F ratio during MV

 

112 (72–231)

  
  1. Data as median (IQR) unless specified otherwise
  2. PRISM Pediatric Risk of Mortality, Hb haemoglobin, RDW Red cell Distribution Width, ICU Intensive Care Unit, MV mechanical ventilation, P/F PaO2 / FiO2, 28 day VFD 28 day ventilator-free days, LOS length of stay. Mean difference versus non-ventilated subgroup (data not shown)