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Table 2 Effect of RSV (5, 10 and 20 mg/kg) on escape latency (sec)

From: Resveratrol protects against ICV collagenase-induced neurobehavioral and biochemical deficits

Groups

Day 23

Day 24

Day 25

Day 26

Day 27

Control

85.6 ± 2.55

72.4 ± 7.99

41.2 ± 9.20

36.4 ± 4.74

13.2 ± 3.59

SHAM

83.2 ± 4.90

74.2 ± 5.87

44.2 ± 9.46

44.6 ± 11.29

21.8 ± 4.21

Control + RSV (40 mg/kg)

83.9 ± 2.97

65.4 ± 6.07

42.6 ± 9.23

25.4 ± 4.64

11.6 ± 4.4

ICV-Collagenase (1 IU)

87.4 ± 1.78

80.8 ± 4.37

75.2 ± 5.32#

69.4 ± 9.42#

65.6 ± 10.32#

ICH + RSV (5 mg/kg)

83.6 ± 4.23

80.4 ± 5.07

60.8 ± 8.08

48.2 ± 11.55

40.7 ± 12.4

ICH + RSV (10 mg/kg)

79.6 ± 8.77

72.4 ± 9.04

49.3 ± 11.63

35.8 ± 9.23

26.8 ± 5.26*

ICH + RSV (20 mg/kg)

81.6 ± 8.17

66 ± 6.56

32.6 ± 6.45*

22.8 ± 2.74*

16.4 ± 2.78*

  1. Values are expressed as mean ± SEM. ICH indicates ICV-COL treated rats; RSV, resveratrol. One way ANOVA followed by Tukey’s multiple comparison tests was applied. #p < 0.05 as compared to control group. *p < 0.05 as compared to ICV-COL group. $ p < 0.05 as compared to ICH + RSV (5 mg/kg)