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Table 2 Effect of RSV (5, 10 and 20 mg/kg) on escape latency (sec)

From: Resveratrol protects against ICV collagenase-induced neurobehavioral and biochemical deficits

Groups Day 23 Day 24 Day 25 Day 26 Day 27
Control 85.6 ± 2.55 72.4 ± 7.99 41.2 ± 9.20 36.4 ± 4.74 13.2 ± 3.59
SHAM 83.2 ± 4.90 74.2 ± 5.87 44.2 ± 9.46 44.6 ± 11.29 21.8 ± 4.21
Control + RSV (40 mg/kg) 83.9 ± 2.97 65.4 ± 6.07 42.6 ± 9.23 25.4 ± 4.64 11.6 ± 4.4
ICV-Collagenase (1 IU) 87.4 ± 1.78 80.8 ± 4.37 75.2 ± 5.32# 69.4 ± 9.42# 65.6 ± 10.32#
ICH + RSV (5 mg/kg) 83.6 ± 4.23 80.4 ± 5.07 60.8 ± 8.08 48.2 ± 11.55 40.7 ± 12.4
ICH + RSV (10 mg/kg) 79.6 ± 8.77 72.4 ± 9.04 49.3 ± 11.63 35.8 ± 9.23 26.8 ± 5.26*
ICH + RSV (20 mg/kg) 81.6 ± 8.17 66 ± 6.56 32.6 ± 6.45* 22.8 ± 2.74* 16.4 ± 2.78*
  1. Values are expressed as mean ± SEM. ICH indicates ICV-COL treated rats; RSV, resveratrol. One way ANOVA followed by Tukey’s multiple comparison tests was applied. #p < 0.05 as compared to control group. *p < 0.05 as compared to ICV-COL group. $ p < 0.05 as compared to ICH + RSV (5 mg/kg)