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Table 1 Patients’ characteristics and clinical data (Groups with significant differences are marked by an asterisk; one-way ANOVA)

From: Increased adipose tissue expression of TLR8 in obese individuals with or without type-2 diabetes: significance in metabolic inflammation

Parameter

Non-diabetic

Diabetic

Lean

Overweight

Obese

Lean

Overweight

Obese

Total number (N)

9

17

23

3

10

32

Male (N)

3

11

13

2

6

18

Female (N)

6

6

10

1

4

14

Age (Yrs.)

25–53

29–71

26–66

48–58

45–59

23–72

Body mass index (kg/m2)

22.47 ± 2.52*

28.36 ± 1.10*

35.00 ± 3.45*

25.47 ± 0.34

27.87 ± 1.70

33.69 ± 2.55

Body fat percentage

27.73 ± 6.09

33.04 ± 4.95

39.09 ± 4.29

32.10 ± 6.22

31.29 ± 6.08

37.33 ± 5.04

Glucose (mmol/L)

4.94 ± 0.72

5.69 ± 1.63

5.24 ± 0.71

5.80 ± 0.42

9.04 ± 2.22

8.71 ± 2.91

Cholesterol (mmol/L)

5.53 ± 1.04

4.87 ± 0.81

5.05 ± 1.14

5.40 ± 2.55

4.91 ± 1.62

5.03 ± 1.23

High-density lipoprotein (mmol/L)

1.70 ± 0.48

1.20 ± 0.19

1.13 ± 0.24

1.14 ± 0.15

1.12 ± 0.40

1.15 ± 0.30

Low-density lipoprotein (mmol/L)

3.53 ± 0.92

3.14 ± 0.74

3.29 ± 1.01

3.70 ± 2.12

2.89 ± 1.37

2.98 ± 1.10

Triglycerides (mmol/L)

0.64 ± 0.25

1.18 ± 0.67

1.44 ± 0.89

1.25 ± 1.25

1.97 ± 0.83

1.89 ± 1.48

HbA1c (%)

5.74 ± 0.49

5.92 ± 1.70

5.68 ± 0.64

6.00 ± 0.28

7.91 ± 1.96

8.27 ± 1.50

Hypertension (N)

0

2

4

0

3

15

Hyperlipidemia (N)

0

0

1

0

2

4

Coronary artery disease (N)

0

0

1

0

1

1

Allergy (N)

0

0

1

0

0

2

Asthma (N)

1

1

0

0

0

3

Therapy

Ventolin

Nadolol, Zocor, Lipitor, Aspirin

Concor, Lipitor, Aspirin, Diovan, Zyloric

Metfornin, Aspirin

Glucophage, Lipitor, Lantus, Zocor, Diovan, NovoRapid, Metformin, Aspirin

NovoRapid, Lantus, Insulin, Aspirin, Concor, Zocor, Mixtard, Tenormin, Glucophage, Metformin, Capoten