Table 2 Comparison of metformin with other drugs on cytokines
From: Effects of metformin on blood and urine pro-inflammatory mediators in patients with type 2 diabetes
Treatment | N | Serum (pg/ml) | Urine (pm/ml) | ||
|---|---|---|---|---|---|
IL-6 | IL-10 | TNF-α | MCP-1 | ||
Metformin | 54 | 11.27 ± 2.56 | 2.50 ± 0.59 | 11.26 ± 2.14 | 111.28 ± 21.06 |
Gliclazide | 44 | 12.24 ± 2.42 | 2.55 ± 0.69 | 10.89 ± 2.26 | 126.42 ± 28.85** |
Acarbose | 18 | 12.99 ± 2.73* | 2.19 ± 0.74 | 12.62 ± 3.17* | 114.24 ± 22.86 |
Repaglinide | 36 | 13.02 ± 2.78** | 2.56 ± 0.62 | 11.36 ± 1.98 | 123.46 ± 14.30** |